KMLE Medical Dictionary

 
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VIPoma:
A rare pancreatic endocrine tumor producing Vasoactive intestinal protein (VIP). Due to this hormone, the patients suffer from a watery diarrhea and hypokalemia, and they have a diminished gastric acid secretion, hence the acronym Watery Diarrea, Hypokalemia and Achlorhydria (WDHA). The tumor can be malignant and metastasize mainly to the liver. Surgical resection if possible is the treatment of choice and a complete resection is curative. VIPoma is also termed Verner-Morrison syndrome.
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Vipoma:
A tumor that secretes VASOACTIVE INTESTINAL PEPTIDE, a neuropeptide that causes VASODILATION; relaxation of smooth muscles; watery DIARRHEA; HYPOKALEMIA; and HYPOCHLORHYDRIA. Vipomas, derived from the pancreatic ISLET CELLS, generally are malignant and can secrete other hormones. In most cases, Vipomas are located in the PANCREAS but can be found in extrapancreatic sites.
Synonyms: Diarrheogenic Islet Cell Tumor, VIP-Secreting Tumor (VIPoma), Vipoma Syndrome, Cholera, Pancreatic, Diarrhea Syndrome, Watery, Diarrheogenic Tumors, Syndrome, Verner-Morrison, Syndrome, Vipoma, Syndrome, Watery Diarrhea, Tumor, Diarrheogenic, Vipomas
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VIPoma:

 
vasoactive intestinal polypeptide-secreting tumor
 

         
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